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Due to unforeseen circumstances, Alfred's seminar had to be cancelled. We apologize for any inconvenience.
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Speakers' information
Alfred SUN Duke-NUS Medical School "Using human midbrain organoids to understand floor plate DA neuron development and degeneration" |
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ABSTRACT
How human floor plate progenitors form and give rise to midbrain DA neurons that eventually degenerate and cause Parkinson’s disease remain poorly understood. We attempt to address this gap in knowledge by our newly developed 3D human midbrain organoid model. In this talk, I will present our work characterising these organoids and demonstrate that they can reveal pathogenic development in PD patients.
BIO
A native of Hang Zhou, China, Alfred Sun came to Singapore in 1997 and completed his high school before taking up the A*STAR NSS-PhD scholarship. He obtained B.S. from Duke University and Ph.D from Stanford University (Supervisor: Dr. Gerald Crabtree). He then returned to Singapore and joined Prof. Bing Lim’s and later Prof. Ng Huck-Hui’s lab as a postdoc. Prior to starting his own lab in Duke-NUS, Alfred was a junior PI in the National Neuroscience Institute.
How human floor plate progenitors form and give rise to midbrain DA neurons that eventually degenerate and cause Parkinson’s disease remain poorly understood. We attempt to address this gap in knowledge by our newly developed 3D human midbrain organoid model. In this talk, I will present our work characterising these organoids and demonstrate that they can reveal pathogenic development in PD patients.
BIO
A native of Hang Zhou, China, Alfred Sun came to Singapore in 1997 and completed his high school before taking up the A*STAR NSS-PhD scholarship. He obtained B.S. from Duke University and Ph.D from Stanford University (Supervisor: Dr. Gerald Crabtree). He then returned to Singapore and joined Prof. Bing Lim’s and later Prof. Ng Huck-Hui’s lab as a postdoc. Prior to starting his own lab in Duke-NUS, Alfred was a junior PI in the National Neuroscience Institute.